We were always told that if we wanted to recover from a busy day, we just had to follow a basic formula of sleeping for eight hours; drinking more water; and improving our diet. Unfortunately, there are lots of people who will never recover completely by doing those three things. Those people will tell you that they still wake up feeling as “heavy” as they felt when they went to bed, the Mid Afternoon Slump Turns into a Complete Shutdown.
The reality is that if getting sufficient rest does not allow you to feel well-rested, then you have much more to deal with than just your lack of will power. Persistent fatigue serves as a “red flag” for the body, showing us that something more than fatigue is keeping us from returning to base line health. To be able to continue enjoying life in a productive way we need to take steps to correctly identify the physiological barriers to our health recovery.
Hormones act as the body’s chemical messengers, influencing metabolic rate, fertility, clarity of thought, and overall physical stamina. When hormonal communication is out of balance, our capacity to produce energy effectively decreases significantly.
Cortisol is commonly referred to as the “stress hormone” because it produces many of the stress-related feelings we struggle with. Nevertheless, cortisol is actually the energy regulator for our bodies. In a well-functioning body, cortisol levels are highest when we awake in the morning, then gradually decrease during the evening hours.
The thyroid is often considered the “Master Thermostat” of our cells. A person whose thyroid is underactive (hypothyroidism) will experience slowed metabolism throughout the body. A person with hypothyroidism will usually feel fatigued with a heavy “brain fog,” have cold hands and feet, and will feel an overall lethargy which cannot be remedied by any amount of caffeine.
Testosterone and Estrogen are often associated only with reproductive health, but they are critical for muscle mass, density, and metabolic activity. Levels that are too low in either gender can produce serious symptoms including lack of energy, endurance and malaise.
Many patients think their labs are “normal” simply because they are within the broad reference value range, but “normal” does not mean “optimal.” You may feel clinically fatigued even if your blood test indicates that you are at or close to the bottom of the reference value range.
Burnout is typically thought of as either a mental or emotional state, but it is based on biology. The nervous system has built-in adaptations to enable survival during high-stress situations (fight-or-flight) followed by periods of rest (rest and digest).
Burnout can become physiological when the modern lifestyle causes a constant state of heightened awareness (high-alert). When the sympathetic nervous system stays activated, this constantly results in “burnout” of the body’s biological systems (e.g., the adrenal glands and the brain).
Chronic anxiety forces the body to prioritize survival over normal functions like cell repair, digestion, or deep sleep. So the normal energy and nutrients that are available for normal cell repair and recovery, digestion and rest or deep sleep, are now diverted to provide the body energy to deal with an identified threat. This results in long-term (chronic) mitochondrial dysfunction (power source for cells); the cells become unable to produce ATP (energy) as efficiently as they did prior to the development of mitochondria dysfunction.
The first step in treating burnout as a medical condition and not just a personal weakness is to recognize it as a condition that causes damage to the physical body (nervous system).
For most people, the experience of energy is more like a roller coaster than a steady stream. Energy fluctuations are a clear sign of metabolic instability in terms of the body’s handling of glucose and insulin.
After eating foods high in glycemic carbs or eating in ways that cause spikes in glucose levels in the blood quickly, the body compensates for this spike by releasing an inappropriate amount of insulin to clear out the sugars in the bloodstream. If someone is slightly insulin resistant, their body may clear the glucose too effectively, which creates a condition known as reactive hypoglycemia. When blood sugar drops rapidly, it can create feelings of shakiness, irritability, and extreme fatigue.
Most people do not simply crash at 3:00 PM because of the heavy lunch they just had; often, it is a result of their bodies not being able to be flexible in switching from burning glucose to burning fat for energy. When the metabolism is inflexible, then the energy that you are able to generate is dictated solely by your last meal, and so you will tend to have more and more fatigue as your day goes on.
Inflammation is an unavoidable, protective response to trauma, however chronic or ongoing inflammation is similar to running a background application on a smartphone, using power or physiologic resources without providing any value in return.
Inflammation uses a great deal of the body’s energy and resources; in fact, of all bodily systems, the immune system consumes the greatest amount of energy. When the immune system is under constant tread or force due to chronic low-grade inflammation, the immune system siphons energy intended for cognitive or physical activity.
Hormone Imbalances: Hormones such as cortisol and estrogen regulate the inflammatory response, thus low cortisol or estrogen levels will not prevent or control the inflammatory response.
Fatty Tissue: The fatty tissue that we carry in excess can act like an endocrinal organ by producing and secreting inflammatory cytokines causing the entire body to be in a state of constant vigilance and size.
Poor Recovery: Failure to take an adequate rest period or not receiving enough sleep will hinder cleanup crews’ ability (i.e., immune system) to do their job, allowing the accumulation of cellular debris to build up.
Functional deficiencies can inhibit energy production from cells even with a healthy diet, and these micronutrients act as the “spark plug” for fuel to ignite in the cell like in an automobile’s engine. The “Vital Four” are:
Iron – needed for the transport of oxygen to the body. If you have low ferritin levels (which are the form of stored iron), it can make exercising and even simple everyday functions feel hard.
Vitamin B12 – involved in the synthesis of DNA and nerve function, when deficient creates a type of fatigue that makes one feel like their limbs are heavy.
Vitamin D – is classified as a pro-hormone, and more than a vitamin, it regulates over 1000 genes (a lot of them play an important role in mitochondrial function – i.e., energy production).
Magnesium – is key to producing ATP (the body’s energy) and when stressed, your body will dump magnesium, creating an ongoing cycle of fatigue.
When you feel tired and fatigued, the natural response is to increase your sleeping hours or take a vacation but just like sleep, Vacation requires rest but for those individuals who are experiencing chronic fatigue this will not resolve the underlying issue.
If fatigue stems from a physiological imbalance (including Thyroid Conversion, Nutrient Deficiency, and Chronic Inflammation), simply adding more sleep will not correct the energy deficit. What a person may be using as rest provides temporary relief from the physical symptoms of fatigue but it does not provide the necessary steps to return one’s biological systems to create energy.
Instead of addressing their chronic fatigue with proper diagnostic testing and treatment, many people are trying to “biohack” their way out of it by consuming stimulants (caffeine) or taking over-the-counter supplements (which are often marketed for sustained energy) that will give them a temporary bounce (increased level of energy) but will typically just cover up the existing problem.
As a result of using stimulants without treating the root cause of their fatigue they can actually cause further depletion of their Endocrine System (e.g. Thyroid), leading to an even more severe crash later on.
You can’t truly go from surviving to thriving without moving beyond traditional screenings into precision medicine.
In order to recover fully, you must first take a comprehensive look at your individual biology. Evaluation should include analysis of advanced biomarkers that show how the body communicates – (fasting insulin level, complete Thyroid Profile including Reverse T3, Inflammation, and Functional Nutrient Levels).
The recovery of one’s energy must never be viewed as an end point – that is, a point where a Person has reached his/her destination. Instead, Energy Recovery is an on-going process influenced by numerous variables such as environmental factors, Stress and Age; therefore a single blood draw will not provide adequate information.
Therefore, in order to achieve maximum energy recovery, one must continue to be monitored and adjust protocols to fit the Body’s response profile. At LifeBoost Clinic, our focus is to help uncover, assess and address many of the unnoticed underlying reasons for fatigue and burnout that Primary Care clinics ignore.
Chronic low energy should never be dismissed as a “normal” consequence of aging. Fatigue can be a signal of a more serious issue occurring in the body. Seeking medical advice and investigating what your body truly needs can help restore energy. The process begins with identifying the factors behind energy decline and then taking steps to care for the body accordingly.